I-Mutant2.0

I-Mutant2.0 Help
Last Update 27/12/06


 

 Data set used to train and test
the SVM exploiting structural information

PDB
Mutation
RSA(%)
Temperature
pH
Exp-DDG
Pred-Stability
Pred-DDG








1A23
H32L
31.56
30.00
7.00
4.60
Increase
3.44
1A23
H32L
31.56
30.00
7.00
5.30
Increase
3.44
1A23
H32S
31.56
30.00
7.00
3.60
Increase
2.94
1A23
H32S
31.56
30.00
7.00
5.20
Increase
2.94
1A23
H32Y
31.56
30.00
7.00
0.50
Increase
2.70
1A23
H32Y
31.56
30.00
7.00
6.80
Increase
2.70
1A23
H32Y
31.56
30.00
7.00
6.80
Increase
2.70
1AAR
K6E
49.00
25.00
5.00
0.53
Increase
1.01
1AAR
K6Q
49.00
25.00
5.00
0.26
Increase
-0.17
1AAR
F45W
18.49
25.00
5.00
0.32
Decrease
-1.39
1AAR
H68E
40.79
25.00
5.00
0.77
Decrease
0.55
1AAR
H68Q
40.79
25.00
5.00
0.55
Decrease
-0.78
1AAR
K27Q
7.83
25.00
5.00
-1.91
Decrease
-1.91
1AAR
K29N
32.43
25.00
5.00
-1.48
Decrease
-2.30
1AAR
K29Q
32.43
25.00
5.00
-1.67
Decrease
-1.12
1AAR
R42E
36.72
25.00
5.00
1.63
Decrease
-0.38
1AAR
R72Q
51.14
25.00
5.00
-0.33
Decrease
-1.05
1AG2
E200K
79.39
25.00
7.00
-0.14
Decrease
-0.23
1AG2
F198S
6.13
25.00
7.00
-2.46
Decrease
-2.55
1AG2
M129V
44.38
25.00
7.00
-0.33
Decrease
-0.52
1AG2
Q217R
22.96
25.00
7.00
-2.13
Decrease
-0.81
1AG2
R208H
43.23
25.00
7.00
-1.44
Decrease
-1.59
1AG2
T183A
2.45
25.00
7.00
-4.62
Decrease
-0.37
1AG2
T190V
52.56
25.00
7.00
-0.17
Increase
-0.94
1AG2
V180I
27.00
25.00
7.00
-0.50
Decrease
-1.08
1AG2
V210I
0.00
25.00
7.00
-0.26
Decrease
-0.81
1AJ3
W22F
32.89
25.00
7.50
-1.11
Decrease
-0.86
1AKK
L94V
2.46
83.00
2.00
-1.20
Decrease
-1.92
1ANK
D84H
8.26
51.80
7.20
-1.40
Decrease
-1.18
1ANK
F86L
1.54
51.80
7.20
-0.80
Decrease
-1.42
1ANK
G85V
9.53
51.80
7.20
-2.40
Increase
1.20
1ANK
R88G
29.34
51.80
7.40
-0.20
Decrease
-1.48
1ARR
P8L
32.63
20.00
7.50
2.40
Decrease
-3.34
1ARR
P8L
32.63
25.00
7.50
2.49
Decrease
-3.29
1ARR
P8L
32.63
53.40
7.50
2.55
Decrease
-2.90
1AYF
C95S
47.01
37.00
8.50
0.96
Decrease
-0.44
1AYF
D76E
60.24
37.00
8.50
0.45
Increase
0.42
1AYF
H56Q
3.08
37.00
8.50
-1.67
Decrease
-1.06
1AYF
H56R
3.08
37.00
8.50
-1.16
Decrease
-2.02
1AYF
H56T
3.08
37.00
8.50
-1.19
Decrease
-1.15
1AYF
T54A
41.24
37.00
8.50
-1.31
Decrease
-0.92
1AYF
T54S
41.24
37.00
8.50
0.05
Decrease
0.06
1AYF
Y82F
63.13
37.00
8.50
-0.01
Decrease
0.34
1AYF
Y82L
63.13
37.00
8.50
-0.36
Decrease
-0.74
1AYF
Y82S
63.13
37.00
8.50
-0.33
Decrease
-1.90
1AYF
Y82W
63.13
37.00
8.50
-0.21
Decrease
-0.91
1BNI
D8A
61.00
25.00
4.40
-0.69
Decrease
-0.81
1BNI
D8A
61.00
25.00
6.30
-0.90
Decrease
-0.86
1BNI
D8G
61.00
25.00
6.30
-1.17
Decrease
-1.25
1BNI
D8S
61.00
25.00
6.30
-0.97
Decrease
-0.70
1BNI
F7L
14.40
25.00
6.15
-4.60
Decrease
-2.17
1BNI
I4A
34.05
25.00
6.30
-1.40
Decrease
-2.45
1BNI
I4V
34.05
25.00
6.30
-0.60
Decrease
-0.02
1BNI
N5A
8.67
25.00
6.30
-1.90
Decrease
-2.67
1BNI
T6A
53.71
25.00
6.30
-2.10
Decrease
-0.81
1BNI
T6A
53.71
25.00
6.30
-2.23
Decrease
-0.81
1BNI
T6A
53.71
25.00
6.30
-2.53
Decrease
-0.81
1BNI
T6D
53.71
25.00
6.30
0.11
Decrease
-0.56
1BNI
T6E
53.71
25.00
6.30
-0.27
Decrease
-0.44
1BNI
T6G
53.71
25.00
6.30
-1.20
Decrease
-1.32
1BNI
T6G
53.71
25.00
6.30
-1.34
Decrease
-1.32
1BNI
T6H
53.71
25.00
4.40
-2.65
Decrease
-2.07
1BNI
T6H
53.71
25.00
8.90
-1.56
Decrease
-1.73
1BNI
T6N
53.71
25.00
6.30
-1.27
Decrease
-1.69
1BNI
T6P
53.71
25.00
6.30
-3.08
Decrease
-2.05
1BNI
T6Q
53.71
25.00
6.30
-1.87
Decrease
-1.54
1BNI
T6S
53.71
25.00
6.30
-0.22
Decrease
-1.70
1BNI
A32C
83.76
25.00
6.30
-1.00
Decrease
-0.40
1BNI
A32D
83.76
25.00
6.30
-0.70
Decrease
-0.16
1BNI
A32E
83.76
25.00
6.30
-0.60
Decrease
-0.18
1BNI
A32F
83.76
25.00
6.30
-0.70
Decrease
-0.73
1BNI
A32G
83.76
25.00
6.30
-0.90
Decrease
-0.94
1BNI
A32H
83.76
25.00
6.30
-0.80
Decrease
-0.44
1BNI
A32I
83.76
25.00
6.30
-0.80
Decrease
-0.46
1BNI
A32K
83.76
25.00
6.30
-0.20
Decrease
-1.23
1BNI
A32L
83.76
25.00
6.30
-0.30
Decrease
-1.05
1BNI
A32M
83.76
25.00
6.30
-0.30
Decrease
-1.01
1BNI
A32N
83.76
25.00
6.30
-0.70
Decrease
-0.15
1BNI
A32P
83.76
25.00
6.30
-4.10
Increase
0.28
1BNI
A32Q
83.76
25.00
6.30
-0.50
Decrease
-0.28
1BNI
A32R
83.76
25.00
6.30
-0.10
Decrease
-0.36
1BNI
A32S
83.76
25.00
6.30
-0.40
Decrease
-0.62
1BNI
A32T
83.76
25.00
6.30
-0.80
Decrease
-0.59
1BNI
A32V
83.76
25.00
6.30
-0.90
Decrease
0.07
1BNI
A32W
83.76
25.00
6.30
-1.00
Decrease
-0.23
1BNI
A32Y
83.76
25.00
6.30
-0.80
Decrease
-0.98
1BNI
D12A
54.20
25.00
6.30
0.43
Decrease
-0.68
1BNI
D12A
54.20
25.00
6.30
-0.30
Decrease
-0.68
1BNI
D12G
54.20
25.00
4.40
-0.78
Decrease
-0.77
1BNI
D12G
54.20
25.00
6.30
-1.29
Decrease
-0.81
1BNI
D12S
54.20
25.00
6.30
-0.65
Decrease
-0.78
1BNI
D22M
94.03
25.00
4.40
-0.27
Increase
-0.19
1BNI
D44E
77.72
25.00
6.30
0.10
Increase
-0.38
1BNI
D54A
19.71
25.00
6.30
-3.00
Decrease
-1.65
1BNI
D54A
19.71
25.00
6.30
-3.30
Decrease
-1.65
1BNI
D54N
19.71
25.00
4.40
-2.46
Decrease
-2.64
1BNI
D54N
19.71
25.00
4.40
-2.65
Decrease
-2.64
1BNI
D54N
19.71
25.00
4.40
-2.66
Decrease
-2.64
1BNI
D54N
19.71
25.00
6.30
-2.40
Decrease
-2.55
1BNI
D54N
19.71
25.00
6.30
-2.60
Decrease
-2.55
1BNI
D54N
19.71
25.00
8.90
-2.32
Decrease
-2.38
1BNI
D75N
0.35
25.00
6.30
-4.80
Decrease
-2.44
1BNI
D75N
0.35
25.00
6.30
-5.00
Decrease
-2.44
1BNI
D93N
47.81
25.00
6.30
-4.11
Decrease
-0.72
1BNI
E29A
48.20
25.00
6.30
-1.25
Decrease
-0.71
1BNI
E29G
48.20
25.00
6.30
-1.80
Decrease
-0.23
1BNI
E29G
48.20
25.00
6.30
-1.81
Decrease
-0.23
1BNI
E29Q
48.08
25.00
6.30
0.00
Decrease
-1.47
1BNI
E29S
48.20
25.00
6.30
-1.23
Decrease
-0.88
1BNI
E73A
6.70
25.00
6.30
-2.50
Decrease
-1.56
1BNI
G34A
48.92
25.00
6.30
-3.12
Increase
-1.14
1BNI
G34D
48.92
25.00
6.30
-3.39
Decrease
-2.11
1BNI
G34H
48.92
25.00
4.40
-2.60
Decrease
-2.29
1BNI
G34H
48.92
25.00
6.30
-2.65
Decrease
-2.24
1BNI
G34H
48.92
25.00
8.90
-3.15
Decrease
-2.14
1BNI
G34K
48.92
25.00
6.30
-3.12
Decrease
-2.44
1BNI
G34N
48.92
25.00
6.30
-2.75
Decrease
-2.41
1BNI
G34R
48.92
25.00
6.30
-2.42
Decrease
-1.97
1BNI
G34S
48.92
25.00
6.30
-3.20
Decrease
-2.10
1BNI
G34T
48.92
25.00
6.30
-3.37
Decrease
-2.89
1BNI
G52A
1.65
54.10
6.30
-5.30
Decrease
-4.63
1BNI
G52V
1.65
54.10
6.30
-8.40
Decrease
-4.12
1BNI
G53A
22.36
54.10
6.30
-3.40
Decrease
-2.97
1BNI
G53V
22.36
54.10
6.30
-7.80
Decrease
-2.59
1BNI
G65S
78.78
25.00
6.30
0.50
Decrease
-1.63
1BNI
H18A
56.40
25.00
6.30
-1.85
Decrease
-1.37
1BNI
H18D
56.40
25.00
6.30
-2.56
Decrease
-0.15
1BNI
H18G
56.40
25.00
5.80
-0.98
Decrease
-2.08
1BNI
H18G
56.40
25.00
6.30
-0.70
Decrease
-2.12
1BNI
H18G
56.40
25.00
9.00
0.51
Decrease
-2.30
1BNI
H18K
56.40
25.00
6.30
-1.19
Decrease
-2.12
1BNI
H18K
56.40
25.00
6.30
-1.20
Decrease
-2.12
1BNI
H18N
56.40
25.00
6.30
-1.68
Decrease
-1.39
1BNI
H18Q
56.40
25.00
6.30
-1.60
Decrease
-1.19
1BNI
H18R
56.40
25.00
6.30
-1.17
Decrease
-0.80
1BNI
H18S
56.40
25.00
6.30
-2.28
Decrease
-1.06
1BNI
I25A
10.76
25.00
6.30
-3.50
Decrease
-2.62
1BNI
I25V
10.76
25.00
6.30
-1.10
Decrease
-1.24
1BNI
I51A
0.11
25.00
6.30
-4.70
Decrease
-3.64
1BNI
I51V
0.11
25.00
4.40
-1.86
Decrease
-1.85
1BNI
I51V
0.11
25.00
6.30
-1.80
Decrease
-1.80
1BNI
I55A
51.89
25.00
6.30
-1.10
Decrease
-2.30
1BNI
I55T
51.89
25.00
6.30
-0.60
Decrease
-1.66
1BNI
I55V
51.89
25.00
6.30
-0.30
Decrease
0.41
1BNI
I55V
51.89
25.00
6.30
-0.30
Decrease
0.41
1BNI
I76A
0.00
25.00
6.30
-1.90
Decrease
-3.75
1BNI
I76V
0.00
25.00
6.30
-0.80
Decrease
-1.93
1BNI
I88A
0.00
25.00
6.30
-4.00
Decrease
-2.72
1BNI
I88A
0.00
25.00
6.30
-4.46
Decrease
-2.72
1BNI
I88A
0.00
25.00
6.30
-4.46
Decrease
-2.72
1BNI
I88A
0.00
48.00
6.30
-3.90
Decrease
-2.49
1BNI
I88L
0.00
25.00
6.30
-0.30
Decrease
-1.03
1BNI
I88V
0.00
25.00
4.40
-1.47
Decrease
-1.55
1BNI
I88V
0.00
25.00
6.30
-1.30
Decrease
-1.45
1BNI
I88V
0.00
25.00
6.30
-1.49
Decrease
-1.45
1BNI
I88V
0.00
25.00
6.30
-1.49
Decrease
-1.45
1BNI
I88V
0.00
48.00
6.30
-1.10
Decrease
-1.35
1BNI
I96A
0.00
25.00
6.30
-3.20
Decrease
-3.85
1BNI
I96A
0.00
25.00
6.30
-3.33
Decrease
-3.85
1BNI
I96A
0.00
25.00
6.30
-3.52
Decrease
-3.85
1BNI
I96A
0.00
25.00
6.30
-3.52
Decrease
-3.85
1BNI
I96A
0.00
25.00
6.30
-4.00
Decrease
-3.85
1BNI
I96A
0.00
48.00
6.30
-3.20
Decrease
-3.54
1BNI
I96V
0.00
25.00
4.40
-1.17
Decrease
-1.25
1BNI
I96V
0.00
25.00
4.40
-1.18
Decrease
-1.25
1BNI
I96V
0.00
25.00
6.30
-0.90
Decrease
-1.30
1BNI
I96V
0.00
25.00
6.30
-0.95
Decrease
-1.30
1BNI
I96V
0.00
25.00
6.30
-0.98
Decrease
-1.30
1BNI
I96V
0.00
25.00
6.30
-0.98
Decrease
-1.30
1BNI
I96V
0.00
25.00
6.30
-1.10
Decrease
-1.30
1BNI
I96V
0.00
48.00
6.30
-0.90
Decrease
-1.07
1BNI
K19R
35.00
25.00
6.30
0.20
Decrease
-1.85
1BNI
K27G
32.96
25.00
6.30
-0.40
Decrease
-1.59
1BNI
K27G
32.96
25.00
6.30
-0.55
Decrease
-1.59
1BNI
K62R
42.29
25.00
6.30
-0.50
Increase
1.08
1BNI
K62R
42.68
25.00
6.30
-0.40
Increase
1.08
1BNI
K66A
63.20
25.00
6.30
0.20
Increase
-0.93
1BNI
L14A
0.00
25.00
6.30
-4.30
Decrease
-3.97
1BNI
L14A
0.00
25.00
6.30
-4.80
Decrease
-3.97
1BNI
L14A
0.00
25.00
6.30
-4.80
Decrease
-3.97
1BNI
L14A
0.00
48.00
6.30
-4.20
Decrease
-3.57
1BNI
L33Q
52.10
25.00
6.30
-1.30
Decrease
-0.66
1BNI
L89T
0.00
25.00
6.30
-2.50
Decrease
-2.91
1BNI
L89V
0.00
25.00
6.30
-0.30
Decrease
-1.72
1BNI
L89V
0.00
25.00
6.30
-0.30
Decrease
-1.72
1BNI
N23A
9.29
25.00
6.30
-2.20
Decrease
-0.57
1BNI
N41D
18.92
25.00
6.30
-2.50
Increase
-0.55
1BNI
N58A
15.92
25.00
6.30
-2.70
Decrease
-1.27
1BNI
N58D
15.92
25.00
6.30
0.50
Decrease
-2.37
1BNI
N77A
48.70
25.00
6.30
-1.60
Decrease
-1.64
1BNI
N84A
34.70
25.00
6.30
-2.00
Decrease
-1.65
1BNI
Q15I
38.63
25.00
6.30
1.00
Decrease
0.40
1BNI
Q31A
56.77
25.00
6.30
0.10
Decrease
0.33
1BNI
Q31A
56.77
25.00
6.30
0.10
Decrease
0.33
1BNI
Q31G
56.77
25.00
6.30
-0.98
Decrease
-0.32
1BNI
Q31S
56.77
25.00
6.30
-0.20
Decrease
-0.71
1BNI
Q31S
56.77
25.00
6.30
-0.20
Decrease
-0.71
1BNI
Q31S
56.77
25.00
6.30
-0.25
Decrease
-0.71
1BNI
R69K
15.81
25.00
6.30
-3.13
Decrease
-3.29
1BNI
R69M
15.81
25.00
4.40
-2.86
Decrease
-1.52
1BNI
R69M
15.81
25.00
6.30
-2.12
Decrease
-1.52
1BNI
R69S
15.81
25.00
6.30
-2.72
Decrease
-1.47
1BNI
R83K
29.13
25.00
6.30
-4.13
Decrease
-1.68
1BNI
R83Q
29.13
25.00
4.40
-1.58
Decrease
-2.70
1BNI
R83Q
29.13
25.00
6.30
-2.05
Decrease
-2.62
1BNI
S28A
66.98
25.00
6.30
0.41
Increase
-0.46
1BNI
S28E
66.98
25.00
6.30
0.40
Increase
-0.08
1BNI
S28G
66.98
25.00
6.30
-0.45
Increase
-0.17
1BNI
S85A
23.89
25.00
6.30
-0.12
Decrease
-1.98
1BNI
S91A
0.94
25.00
4.40
-1.16
Decrease
-2.91
1BNI
S91A
0.94
25.00
4.40
-1.38
Decrease
-2.91
1BNI
S91A
0.94
25.00
6.30
-1.90
Decrease
-2.93
1BNI
S92A
47.27
25.00
4.40
-2.83
Decrease
-0.65
1BNI
S92A
47.27
25.00
6.30
-2.80
Decrease
-0.77
1BNI
T16A
75.20
25.00
6.30
-0.27
Decrease
-1.41
1BNI
T16G
75.20
25.00
6.30
-1.66
Decrease
-1.00
1BNI
T16R
75.20
25.00
4.40
0.20
Decrease
-0.70
1BNI
T16R
75.20
25.00
6.30
0.50
Decrease
-0.54
1BNI
T16R
75.20
25.00
6.30
0.50
Decrease
-0.54
1BNI
T16R
75.20
25.00
6.30
-0.48
Decrease
-0.54
1BNI
T16S
75.20
25.00
6.30
-1.70
Decrease
-0.17
1BNI
T16S
75.20
25.00
6.30
-1.87
Decrease
-0.17
1BNI
T26A
28.48
25.00
6.30
-1.90
Decrease
-2.02
1BNI
T26A
28.48
25.00
6.30
-2.11
Decrease
-2.02
1BNI
T26A
28.48
25.00
6.30
-2.14
Decrease
-2.02
1BNI
T26D
28.48
25.00
6.30
-0.08
Decrease
-1.62
1BNI
T26E
28.48
25.00
6.30
-0.05
Decrease
-0.57
1BNI
T26G
28.48
25.00
4.40
-2.08
Decrease
-1.55
1BNI
T26G
28.48
25.00
6.30
-1.50
Decrease
-1.47
1BNI
T26G
28.48
25.00
6.30
-1.58
Decrease
-1.47
1BNI
T26N
28.48
25.00
6.30
-1.29
Decrease
-1.50
1BNI
T26Q
28.48
25.00
6.30
-1.72
Decrease
-1.34
1BNI
T26S
28.48
25.00
6.30
-0.56
Decrease
-1.00
1BNI
T26V
28.48
25.00
6.30
-2.31
Decrease
-0.47
1BNI
T79V
78.59
25.00
6.30
0.30
Decrease
-0.82
1BNI
T99V
1.23
25.00
6.30
-2.70
Decrease
-1.67
1BNI
V10A
0.00
25.00
6.30
-3.40
Decrease
-3.14
1BNI
V10T
0.00
25.00
6.30
-2.50
Decrease
-3.34
1BNI
V36A
46.71
25.00
6.30
-1.30
Decrease
-0.77
1BNI
V36T
46.71
25.00
6.30
-1.10
Decrease
-1.96
1BNI
V45A
27.91
25.00
6.30
-1.80
Decrease
-0.54
1BNI
V45T
27.91
25.00
6.30
-2.40
Decrease
-0.98
1BNI
W94F
29.48
25.00
5.80
-1.06
Decrease
-1.31
1BNI
W94F
29.48
25.00
9.00
-0.60
Decrease
-1.20
1BNI
W94L
29.48
25.00
5.80
-1.59
Decrease
-1.50
1BNI
W94L
29.48
25.00
8.90
-0.64
Decrease
-1.45
1BNI
W94L
29.48
25.00
9.00
-0.66
Decrease
-1.45
1BNI
W94Y
29.48
25.00
5.80
-1.27
Decrease
-1.45
1BNI
W94Y
29.48
25.00
9.00
-0.99
Decrease
-1.35
1BNI
Y13A
18.30
25.00
6.30
-3.30
Decrease
-2.37
1BNI
Y13A
18.30
25.00
6.30
-3.71
Decrease
-2.37
1BNI
Y13F
18.30
25.00
6.30
-0.41
Decrease
-0.05
1BNI
Y17A
56.62
25.00
6.30
-2.00
Decrease
-1.30
1BNI
Y17A
56.62
25.00
6.30
-2.26
Decrease
-1.30
1BNI
Y17F
56.62
25.00
6.30
-0.30
Decrease
-0.94
1BNI
Y17G
56.62
25.00
6.30
-4.03
Decrease
-1.38
1BNI
Y17S
56.62
25.00
6.30
-2.57
Decrease
-1.16
1BNI
Y24F
8.10
25.00
6.30
0.00
Decrease
-2.29
1BNI
Y78F
4.40
25.00
6.30
-1.40
Decrease
0.17
1BNI
Y78F
4.40
25.00
6.30
-1.50
Decrease
0.17
1BNI
I109A
24.32
25.00
6.30
-2.10
Decrease
-2.17
1BNI
I109V
24.32
25.00
6.30
-0.80
Decrease
-0.39
1BNI
K108R
54.93
25.00
6.30
0.90
Decrease
-0.32
1BNI
Q104A
51.51
25.00
6.30
-0.20
Decrease
-0.70
1BNI
R110A
31.31
25.00
6.30
-0.40
Decrease
-1.47
1BNI
T105V
62.29
25.00
6.30
-2.20
Decrease
-0.20
1BNI
Y103F
28.22
25.00
6.30
0.00
Decrease
-1.14
1BPI
D3A
79.67
39.00
7.00
0.20
Decrease
-0.13
1BPI
E7A
26.79
39.00
7.00
-1.50
Decrease
-0.94
1BPI
F4A
10.91
39.00
7.00
-3.00
Decrease
-1.92
1BPI
L6A
60.84
39.00
7.00
-0.60
Decrease
-0.20
1BPI
P2A
47.78
39.00
7.00
-1.30
Decrease
-1.11
1BPI
P8A
76.53
39.00
7.00
-0.30
Decrease
-0.72
1BPI
P9A
34.60
39.00
7.00
-0.80
Decrease
-1.29
1BPI
R1A
63.01
39.00
7.00
-0.50
Decrease
-0.15
1BPI
D50A
36.02
39.00
7.00
-0.40
Decrease
-1.12
1BPI
E49A
65.83
39.00
7.00
-0.20
Decrease
-0.71
1BPI
F22A
11.56
25.00
2.00
-1.20
Decrease
-5.53
1BPI
F22A
11.56
39.00
7.00
-2.00
Decrease
-5.12
1BPI
F45A
10.11
25.00
2.00
-6.90
Decrease
-2.44
1BPI
G12A
21.73
39.00
7.00
-1.80
Decrease
-0.94
1BPI
G28A
53.62
39.00
7.00
-1.00
Decrease
-0.52
1BPI
G36A
0.25
39.00
7.00
-2.10
Decrease
-2.47
1BPI
G36S
0.76
72.60
4.60
-0.70
Decrease
-1.28
1BPI
G37A
43.71
39.00
7.00
-2.30
Decrease
-1.58
1BPI
G37A
43.84
25.00
2.00
-4.90
Decrease
-1.68
1BPI
G56A
23.89
39.00
7.00
-0.20
Decrease
-0.89
1BPI
G57A
54.51
39.00
7.00
-0.20
Decrease
-1.28
1BPI
I18A
36.97
39.00
7.00
-1.50
Decrease
-1.28
1BPI
I19A
58.05
39.00
7.00
-2.10
Decrease
-0.28
1BPI
K15A
90.52
39.00
7.00
-0.40
Increase
0.26
1BPI
K26A
102.24
39.00
7.00
0.00
Increase
-0.94
1BPI
K41A
47.59
39.00
7.00
-0.40
Decrease
-0.76
1BPI
K46A
80.36
39.00
7.00
0.10
Decrease
0.26
1BPI
L29A
60.57
39.00
7.00
0.00
Decrease
-1.22
1BPI
M52A
62.72
39.00
7.00
-1.70
Decrease
-0.67
1BPI
N24A
23.84
39.00
7.00
-2.20
Decrease
-2.35
1BPI
N43G
0.68
25.00
2.00
-5.70
Decrease
-4.35
1BPI
N43G
0.75
25.00
2.00
-5.70
Decrease
-4.35
1BPI
N44A
14.69
39.00
7.00
-3.30
Decrease
-2.71
1BPI
N44G
14.00
25.00
2.00
-4.70
Decrease
-4.44
1BPI
P13A
52.36
39.00
7.00
-1.20
Decrease
-2.70
1BPI
Q31A
36.39
39.00
7.00
-1.00
Decrease
-0.29
1BPI
R17A
89.17
39.00
7.00
-0.30
Decrease
-0.24
1BPI
R20A
15.46
39.00
7.00
-1.80
Decrease
-1.63
1BPI
R39A
80.13
39.00
7.00
0.00
Decrease
-0.14
1BPI
R42A
70.44
39.00
7.00
-0.50
Decrease
-0.46
1BPI
R53A
74.41
39.00
7.00
-0.10
Decrease
-0.06
1BPI
S47A
30.46
39.00
7.00
-1.60
Decrease
0.17
1BPI
T11A
47.44
39.00
7.00
0.00
Decrease
-0.46
1BPI
T32A
56.96
39.00
7.00
-0.10
Decrease
-0.76
1BPI
T54A
36.12
39.00
7.00
-0.10
Decrease
-0.92
1BPI
V34A
40.27
39.00
7.00
-1.20
Decrease
-1.54
1BPI
Y10A
36.59
39.00
7.00
-1.20
Decrease
-1.90
1BPI
Y23A
4.21
25.00
2.00
-5.90
Decrease
-2.66
1BPI
Y35A
6.69
39.00
7.00
-1.10
Decrease
-3.67
1BPI
Y35G
5.80
25.00
2.00
-5.00
Decrease
-3.30
1BPI
Y35G
6.69
25.00
2.00
-5.00
Decrease
-3.27
1BTA
C82A
27.92
25.00
7.40
0.48
Decrease
1.14
1BVC
E4A
70.06
25.00
4.00
-0.55
Decrease
-0.11
1BVC
E4A
70.06
25.00
4.00
-0.70
Decrease
-0.11
1BVC
L9A
30.58
82.20
9.60
-0.40
Decrease
-0.68
1BVC
Q8A
45.86
4.00
4.20
0.89
Decrease
-0.01
1BVC
Q8A
45.86
4.00
4.20
1.07
Decrease
-0.01
1BVC
Q8G
45.86
4.00
4.20
-0.50
Decrease
-0.72
1BVC
Q8G
45.86
4.00
4.20
-0.63
Decrease
-0.72
1BVC
W7F
7.28
4.00
7.80
0.10
Decrease
-0.94
1BVC
W7F
7.28
4.00
7.80
-0.90
Decrease
-0.94
1BVC
W7F
7.28
4.00
7.80
-1.10
Decrease
-0.94
1BVC
D44A
73.42
25.00
4.00
-0.15
Decrease
-0.70
1BVC
D44A
73.42
25.00
4.00
-0.20
Decrease
-0.70
1BVC
D60A
38.24
25.00
4.00
-0.10
Decrease
-1.16
1BVC
D60A
38.24
25.00
4.00
-0.15
Decrease
-1.16
1BVC
E18A
44.88
25.00
4.00
-0.50
Decrease
-0.32
1BVC
E18A
44.88
25.00
4.00
-0.70
Decrease
-0.32
1BVC
G23A
20.33
82.20
9.60
-1.10
Decrease
0.41
1BVC
H36Q
23.97
4.00
7.80
-0.10
Increase
-0.29
1BVC
H36Q
23.97
4.00
7.80
-0.70
Increase
-0.29
1BVC
H36Q
23.97
4.00
7.80
-0.80
Increase
-0.29
1BVC
I28A
0.97
76.50
11.00
-1.30
Decrease
-1.63
1BVC
I28L
0.97
76.50
11.00
-0.60
Decrease
-0.35
1BVC
I28M
0.97
76.50
11.00
-0.60
Decrease
-0.50
1BVC
I28V
0.97
76.50
11.00
0.00
Decrease
0.03
1BVC
K56A
58.63
25.00
4.00
-0.20
Decrease
-0.04
1BVC
K56A
58.63
25.00
4.00
-0.25
Decrease
-0.04
1BVC
K77A
49.00
25.00
4.00
-0.02
Increase
0.79
1BVC
K77A
49.00
25.00
4.00
-0.05
Increase
0.79
1BVC
L11A
24.03
82.20
9.60
-0.40
Decrease
-0.96
1BVC
L29A
2.62
76.50
11.00
-2.40
Decrease
-1.99
1BVC
L29I
2.62
76.50
11.00
-1.10
Decrease
-1.06
1BVC
L29M
2.62
76.50
11.00
0.10
Decrease
-1.19
1BVC
L29V
2.62
76.50
11.00
-1.70
Decrease
-0.29
1BVC
L49I
3.28
76.50
11.00
-0.80
Decrease
-0.70
1BVC
L69A
0.60
76.50
11.00
-1.20
Decrease
-1.86
1BVC
L69I
0.60
76.50
11.00
0.00
Decrease
0.03
1BVC
L69M
0.60
76.50
11.00
0.00
Decrease
0.10
1BVC
L69V
0.60
76.50
11.00
-0.10
Decrease
-1.08
1BVC
P88A
52.85
82.20
9.60
0.60
Decrease
-0.98
1BVC
T51A
46.14
82.20
9.60
-1.40
Decrease
-0.06
1BVC
T67A
66.33
82.20
9.60
-0.30
Decrease
0.28
1BVC
V13A
0.00
82.20
9.60
-0.70
Decrease
-0.10
1BVC
V66A
37.09
82.20
9.60
0.80
Decrease
-1.31
1BVC
V68T
20.30
4.00
7.80
-0.20
Decrease
-2.71
1BVC
V68T
20.30
4.00
7.80
-0.40
Decrease
-2.71
1BVC
V68T
20.30
4.00
7.80
-0.60
Decrease
-2.71
1BVC
W14F
1.08
4.00
7.80
-0.50
Decrease
-1.29
1BVC
W14F
1.08
4.00
7.80
-0.60
Decrease
-1.29
1BVC
W14F
1.08
4.00
7.80
-1.10
Decrease
-1.29
1BVC
A130K
0.00
4.00
7.80
-0.90
Decrease
-3.02
1BVC
A130K
0.00
4.00
7.80
-1.20
Decrease
-3.02
1BVC
A130K
0.00
4.00
7.80
-2.10
Decrease
-3.02
1BVC
A130L
0.00
4.00
7.80
0.10
Decrease
0.81
1BVC
A130L
0.00
4.00
7.80
-0.90
Decrease
0.81
1BVC
A130L
0.00
4.00
7.80
-1.00
Decrease
0.81
1BVC
E109A
56.84
4.00
4.20
0.17
Decrease
-0.84
1BVC
E109A
56.84
4.00
4.20
0.36
Decrease
-0.84
1BVC
E109G
56.84
4.00
4.20
-0.89
Decrease
-0.76
1BVC
E109G
56.84
4.00
4.20
-0.96
Decrease
-0.76
1BVC
F123K
0.50
4.00
7.80
-0.70
Decrease
-3.01
1BVC
F123K
0.50
4.00
7.80
-1.40
Decrease
-3.01
1BVC
F123K
0.50
4.00
7.80
-2.10
Decrease
-3.01
1BVC
G129A
36.85
82.20
9.60
1.10
Decrease
-0.38
1BVC
H116A
49.48
82.20
9.60
0.20
Increase
0.88
1BVC
I111A
2.70
76.50
11.00
-1.80
Decrease
-2.41
1BVC
I111L
2.70
76.50
11.00
-0.60
Decrease
-0.66
1BVC
I111M
2.70
76.50
11.00
-1.10
Decrease
-1.02
1BVC
I142A
0.00
82.20
9.60
-1.90
Decrease
-1.29
1BVC
I142A
0.16
76.50
11.00
-1.10
Decrease
-1.34
1BVC
I142L
0.16
76.50
11.00
0.60
Decrease
0.26
1BVC
I142M
0.16
76.50
11.00
0.90
Decrease
-0.55
1BVC
I142V
0.16
76.50
11.00
-0.10
Decrease
-0.13
1BVC
K140A
63.98
4.00
4.20
0.35
Decrease
-0.46
1BVC
K140A
63.98
4.00
4.20
0.60
Decrease
-0.46
1BVC
L135I
1.04
76.50
11.00
-1.50
Decrease
-1.51
1BVC
L135M
1.04
76.50
11.00
-0.80
Decrease
-0.51
1BVC
L135V
1.04
76.50
11.00
-2.20
Decrease
-1.66
1BVC
L137A
12.02
82.20
9.60
-1.80
Decrease
-1.12
1BVC
L149A
32.22
82.20
9.60
-1.60
Decrease
-0.67
1BVC
M131A
0.00
4.00
7.80
-0.90
Decrease
-2.36
1BVC
M131A
0.00
4.00
7.80
-1.30
Decrease
-2.36
1BVC
M131A
0.00
4.00
7.80
-2.20
Decrease
-2.36
1BVC
S117A
63.99
82.20
9.60
-0.30
Decrease
-0.87
1BVC
V114A
6.51
82.20
9.60
-1.40
Decrease
-1.63
1C2R
G34S
15.76
30.00
7.50
-2.20
Decrease
-2.25
1C2R
K12D
39.38
25.00
7.50
-1.30
Increase
-0.30
1C2R
K14E
47.16
25.00
7.50
-1.30
Decrease
-0.04
1C2R
K32E
69.03
25.00
7.50
0.20
Increase
-1.06
1C2R
P35A
17.05
30.00
7.50
-2.00
Decrease
-1.31
1C9O
Q2L
38.69
70.00
7.00
0.29
Increase
0.38
1C9O
Q2L
38.69
70.00
7.00
0.29
Increase
0.38
1C9O
Q2L
38.69
70.00
7.00
0.55
Increase
0.38
1C9O
Q2L
38.69
70.00
7.00
0.55
Increase
0.38
1C9O
R3A
67.29
70.00
7.00
-1.05
Decrease
-0.45
1C9O
R3A
67.29
70.00
7.00
-1.89
Decrease
-0.45
1C9O
R3E
67.29
70.00
7.00
-1.00
Decrease
-0.37
1C9O
R3E
67.29
70.00
7.00
-1.00
Decrease
-0.37
1C9O
R3E
67.29
70.00
7.00
-2.75
Decrease
-0.37
1C9O
R3E
67.29
70.00
7.00
-2.75
Decrease
-0.37
1C9O
R3K
67.29
70.00
7.00
-0.14
Decrease
-0.63
1C9O
R3K
67.29
70.00
7.00
-0.19
Decrease
-0.63
1C9O
R3L
67.29
70.00
7.00
-0.22
Decrease
-0.20
1C9O
R3L
67.29
70.00
7.00
-0.93
Decrease
-0.20
1C9O
E46A
32.05
70.00
7.00
-0.12
Decrease
-0.76
1C9O
E46A
32.05
70.00
7.00
-0.12
Decrease
-0.76
1C9O
E46A
32.05
70.00
7.00
-0.22
Decrease
-0.76
1C9O
E46A
32.05
70.00
7.00
-0.22
Decrease
-0.76
1C9O
G23Q
58.58
70.00
7.00
-0.29
Decrease
-0.67
1C9O
G23Q
58.58
70.00
7.00
-0.29
Decrease
-0.67
1C9O
G23Q
58.58
70.00
7.00
-0.31
Decrease
-0.67
1C9O
G23Q
58.58
70.00
7.00
-0.31
Decrease
-0.67
1C9O
L66E
61.22
70.00
7.00
-1.24
Decrease
-0.78
1C9O
L66E
61.22
70.00
7.00
-1.24
Decrease
-0.78
1C9O
L66E
61.22
70.00
7.00
-1.27
Decrease
-0.78
1C9O
L66E
61.22
70.00
7.00
-1.27
Decrease
-0.78
1C9O
N11S
50.89
70.00
7.00
0.22
Increase
0.65
1C9O
N11S
50.89
70.00
7.00
0.22
Increase
0.65
1C9O
N11S
50.89
70.00
7.00
0.33
Increase
0.65
1C9O
N11S
50.89
70.00
7.00
0.33
Increase
0.65
1C9O
Q53E
58.85
70.00
7.00
0.00
Increase
-0.15
1C9O
Q53E
58.85
70.00
7.00
0.00
Increase
-0.15
1C9O
Q53E
58.85
70.00
7.00
-0.10
Increase
-0.15
1C9O
Q53E
58.85
70.00
7.00
-0.10
Increase
-0.15
1C9O
S24D
82.85
70.00
7.00
0.19
Increase
0.64
1C9O
S24D
82.85
70.00
7.00
0.19
Increase
0.64
1C9O
S24D
82.85
70.00
7.00
0.22
Increase
0.64
1C9O
S24D
82.85
70.00
7.00
0.22
Increase
0.64
1C9O
T31S
22.13
70.00
7.00
0.17
Decrease
0.05
1C9O
T31S
22.13
70.00
7.00
0.17
Decrease
0.05
1C9O
T31S
22.13
70.00
7.00
0.19
Decrease
0.05
1C9O
T31S
22.13
70.00
7.00
0.19
Decrease
0.05
1C9O
V64T
40.34
70.00
7.00
-0.19
Decrease
-1.29
1C9O
V64T
40.34
70.00
7.00
-0.19
Decrease
-1.29
1C9O
V64T
40.34
70.00
7.00
-0.26
Decrease
-1.29
1C9O
V64T
40.34
70.00
7.00
-0.26
Decrease
-1.29
1C9O
Y15F
31.07
70.00
7.00
0.07
Increase
0.92
1C9O
Y15F
31.07
70.00
7.00
0.07
Increase
0.92
1C9O
Y15F
31.07
70.00
7.00
-0.05
Increase
0.92
1C9O
Y15F
31.07
70.00
7.00
-0.05
Increase
0.92
1CAH
W5F
26.86
23.00
7.50
0.10
Decrease
0.05
1CAH
W5F
26.86
23.00
7.50
-2.50
Decrease
0.05
1CAH
W16F
1.58
23.00
7.50
0.30
Decrease
-0.62
1CAH
W16F
1.58
23.00
7.50
-6.30
Decrease
-0.62
1CAH
C206S
6.41
23.00
7.50
0.10
Decrease
-2.84
1CAH
C206S
6.41
23.00
7.50
-0.70
Decrease
-2.84
1CHK
W28F
10.48
42.70
7.00
-3.56
Decrease
-2.34
1CHK
W28F
10.48
43.20
7.00
-4.43
Decrease
-2.33
1CHK
W28F
10.48
52.20
7.00
-1.76
Decrease
-2.25
1CHK
W101F
0.00
42.70
7.00
-3.91
Decrease
-1.20
1CHK
W101F
0.00
43.20
7.00
-4.27
Decrease
-1.20
1CHK
W101F
0.00
52.20
7.00
-1.89
Decrease
-1.15
1CHK
W227F
3.62
42.70
7.00
-2.97
Decrease
-1.55
1CHK
W227F
3.62
43.20
7.00
-2.51
Decrease
-1.55
1CHK
W227F
3.62
52.20
7.00
-1.31
Decrease
-1.54
1CSP
E3L
44.88
70.00
7.00
0.41
Increase
1.41
1CSP
E3L
44.88
70.00
7.00
1.60
Increase
1.41
1CSP
E3R
44.88
70.00
7.00
0.77
Increase
-0.11
1CSP
E3R
44.88
70.00
7.00
0.77
Increase
-0.11
1CSP
E3R
44.88
70.00
7.00
2.66
Increase
-0.11
1CSP
E3R
44.88
70.00
7.00
2.66
Increase
-0.11
1CSP
E66L
26.79
70.00
7.00
1.44
Increase
1.91
1CSP
E66L
26.79
70.00
7.00
1.44
Increase
1.91
1CSP
E66L
26.79
70.00
7.00
2.11
Increase
1.91
1CSP
E66L
26.79
70.00
7.00
2.11
Increase
1.91
1CSP
F15A
27.40
60.00
7.00
-1.67
Decrease
-0.52
1CSP
F17A
29.55
60.00
7.00
-1.34
Decrease
-0.46
1CSP
F27A
35.72
60.00
7.00
-0.69
Decrease
-1.36
1CSP
F38A
80.52
60.00
7.00
0.31
Decrease
-0.94
1CYO
F35H
9.92
66.20
7.00
-2.82
Decrease
-1.98
1CYO
F35L
9.92
66.20
7.00
-1.87
Increase
-0.64
1CYO
F35Y
9.92
66.20
7.00
0.79
Decrease
-0.31
1CYO
V45E
50.81
66.70
7.00
-2.68
Decrease
-1.11
1CYO
V45E
50.81
77.60
7.00
-2.06
Decrease
-1.14
1CYO
V45G
50.81
25.00
7.00
-1.91
Decrease
-3.07
1CYO
V45H
50.81
25.00
7.00
-1.65
Decrease
-2.27
1CYO
V45H
50.81
66.70
7.00
-1.34
Decrease
-2.46
1CYO
V45H
50.81
77.60
7.00
-1.39
Decrease
-2.48
1CYO
V45T
50.81
25.00
7.00
-0.96
Decrease
-0.93
1CYO
V45Y
50.81
66.70
7.00
-1.53
Decrease
-0.54
1CYO
V45Y
50.81
77.60
7.00
-1.56
Decrease
-0.56
1CYO
V61E
72.93
25.00
7.00
-1.05
Decrease
-1.48
1CYO
V61E
72.93
67.20
7.00
-1.10
Decrease
-1.51
1CYO
V61H
72.93
25.00
7.00
-1.60
Decrease
-0.61
1CYO
V61H
72.93
67.20
7.00
-1.63
Decrease
-0.29
1CYO
V61K
72.93
25.00
7.00
-2.39
Decrease
-0.68
1CYO
V61K
72.93
67.20
7.00
-2.34
Decrease
-0.64
1CYO
V61Y
72.93
25.00
7.00
-1.34
Decrease
-1.30
1CYO
V61Y
72.93
67.20
7.00
-1.29
Decrease
-1.25
1EL1
A93S
57.26
66.40
4.50
-0.26
Decrease
0.44
1EL1
H21G
57.50
66.40
4.50
-0.48
Increase
0.16
1EL1
I56L
0.05
66.40
4.50
-0.24
Decrease
-0.51
1EL1
V109K
7.09
66.40
4.50
-0.43
Decrease
-1.04
1EM7
I6N
24.00
25.00
5.20
2.07
Decrease
0.56
1EM7
I6N
24.00
63.00
5.20
1.82
Increase
0.24
1EM7
I6T
24.00
25.00
5.20
2.00
Increase
-0.16
1EM7
I6T
24.00
63.00
5.20
1.76
Increase
-0.11
1EM7
T53F
32.59
25.00
5.20
4.61
Increase
2.11
1EM7
T53F
32.59
63.00
5.20
4.10
Increase
1.93
1EM7
T53I
32.59
25.00
5.20
3.30
Increase
2.02
1EM7
T53I
32.59
63.00
5.20
3.81
Increase
2.12
1EM7
T53V
32.59
25.00
5.20
2.80
Increase
1.42
1EM7
T53V
32.59
63.00
5.20
3.38
Increase
1.56
1EM7
T53Y
32.59
25.00
5.20
4.10
Increase
2.31
1EM7
T53Y
32.59
63.00
5.20
4.29
Increase
2.34
1G6N
S128A
10.07
20.00
7.90
-0.26
Decrease
0.00
1G6N
S128P
10.07
20.00
7.90
0.14
Increase
-2.80
1HFY
A30I
0.00
20.00
2.00
0.30
Increase
1.84
1HFY
A30T
0.00
20.00
2.00
0.06
Decrease
-0.72
1HFY
T29I
0.00
20.00
2.00
0.12
Increase
0.15
1HFY
T33I
13.27
20.00
2.00
0.18
Decrease
-0.31
1HUE
A27S
0.00
63.90
7.00
-1.19
Decrease
-1.23
1HUE
A56S
72.60
63.90
7.00
-0.13
Decrease
1.07
1HUE
M69I
30.58
63.90
7.00
0.00
Increase
0.62
1HUE
S31T
20.65
63.90
7.00
0.41
Increase
0.45
1HUE
V42I
0.20
63.90
7.00
-0.82
Decrease
-0.74
1IGV
D19N
47.54
25.00
7.00
0.74
Increase
0.70
1IGV
E17Q
63.77
25.00
7.00
0.38
Decrease
0.16
1IGV
E26Q
73.55
25.00
7.00
0.09
Decrease
0.34
1IOB
T9A
3.89
25.00
6.50
-0.80
Decrease
-1.06
1IOB
T9G
3.89
25.00
6.50
-2.60
Decrease
-2.55
1IOB
T9L
3.89
25.00
6.50
-0.70
Decrease
-0.65
1IOB
T9Q
3.89
25.00
6.50
-1.90
Decrease
-1.00
1IOB
K97G
44.48
25.00
6.50
-1.20
Decrease
-0.53
1IOB
K97R
44.48
25.00
6.50
-0.50
Decrease
-0.78
1IOB
K97V
44.48
25.00
6.50
0.80
Increase
0.18
1LZ1
A9S
0.00
64.90
2.70
-0.02
Decrease
-1.63
1LZ1
E7Q
30.97
65.00
2.20
0.10
Decrease
-0.48
1LZ1
E7Q
30.97
65.00
2.30
-0.43
Decrease
-0.48
1LZ1
E7Q
30.97
65.00
4.00
-1.44
Decrease
-0.44
1LZ1
E7Q
30.97
65.00
4.50
-1.29
Decrease
-0.43
1LZ1
K1A
34.61
64.90
2.70
-0.60
Decrease
0.22
1LZ1
K1M
34.61
64.90
2.70
-0.12
Increase
0.09
1LZ1
L8T
0.00
64.90
2.70
-3.73
Decrease
-2.58
1LZ1
V2A
69.29
49.20
2.70
-1.51
Decrease
-0.68
1LZ1
V2A
69.42
64.90
2.70
-1.51
Decrease
-0.52
1LZ1
V2D
65.97
64.90
2.70
-1.44
Decrease
-0.53
1LZ1
V2F
69.42
64.90
2.70
-0.86
Decrease
-1.22
1LZ1
V2G
69.42
64.90
2.70
-2.30
Decrease
-0.90
1LZ1
V2I
69.42
64.90
2.70
1.10
Decrease
-0.53
1LZ1
V2L
69.42
64.90
2.70
-0.05
Increase
-0.55
1LZ1
V2M
69.42
64.90
2.70
-0.31
Decrease
-0.40
1LZ1
V2N
65.97
64.90
2.70
-1.34
Decrease
-1.40
1LZ1
V2R
65.97
64.90
2.70
-0.38
Decrease
-0.58
1LZ1
V2S
65.97
64.90
2.70
-1.41
Decrease
-0.54
1LZ1
V2Y
65.97
64.90
2.70
-0.36
Decrease
-0.98
1LZ1
A32L
0.00
64.90
2.70
-0.10
Increase
1.52
1LZ1
A32S
0.00
64.90
2.70
-0.33
Decrease
0.17
1LZ1
A47P
76.50
68.80
2.80
0.10
Increase
0.99
1LZ1
A92S
2.72
64.90
2.70
0.81
Decrease
-1.29
1LZ1
A96M
0.00
64.90
2.70
0.02
Decrease
-0.53
1LZ1
A96S
0.00
64.90
2.70
-1.00
Decrease
-0.88
1LZ1
C77A
14.67
57.00
3.00
-4.60
Decrease
-0.78
1LZ1
D18N
46.56
65.00
2.20
-0.53
Decrease
-0.55
1LZ1
D18N
46.56
65.00
4.00
-1.70
Decrease
-0.63
1LZ1
D49N
50.52
65.00
2.20
0.00
Increase
-0.28
1LZ1
D49N
50.52
65.00
4.00
-1.00
Increase
-0.24
1LZ1
D67N
24.01
65.00
2.20
-0.24
Decrease
-3.28
1LZ1
D67N
24.01
65.00
2.30
-0.26
Decrease
-3.28
1LZ1
D67N
24.01
65.00
4.00
-2.25
Decrease
-3.24
1LZ1
D67N
24.01
65.00
4.50
-1.70
Decrease
-3.22
1LZ1
D91P
34.35
68.80
2.80
-0.40
Decrease
-1.10
1LZ1
E35L
20.03
64.90
2.70
-0.53
Increase
0.71
1LZ1
G37A
49.68
64.90
2.70
-0.29
Decrease
-0.10
1LZ1
G37Q
49.68
64.90
2.70
-0.26
Decrease
-0.12
1LZ1
G37Q
49.68
64.90
2.70
-0.26
Decrease
-0.12
1LZ1
H78A
83.62
64.90
2.70
-0.14
Decrease
-0.18
1LZ1
H78G
83.62
64.90
2.70
-0.12
Decrease
-0.08
1LZ1
H78G
83.62
64.90
2.70
-0.12
Decrease
-0.08
1LZ1
I23A
8.27
64.90
2.70
-2.54
Decrease
-1.12
1LZ1
I23V
6.65
49.20
2.70
-0.41
Decrease
-1.12
1LZ1
I23V
8.27
64.90
2.70
-0.36
Decrease
-0.88
1LZ1
I56A
0.38
64.90
2.70
-3.71
Decrease
-4.22
1LZ1
I56A
0.38
64.90
2.70
-3.71
Decrease
-4.22
1LZ1
I56F
0.38
64.90
2.70
-4.09
Decrease
-1.58
1LZ1
I56L
0.38
64.90
2.70
-0.10
Decrease
-0.01
1LZ1
I56M
0.38
64.90
2.70
-1.77
Decrease
-1.42
1LZ1
I56T
0.38
64.90
2.70
-3.64
Decrease
-4.89
1LZ1
I56T
0.38
64.90
2.70
-3.64
Decrease
-4.89
1LZ1
I56V
0.38
49.20
2.70
-1.34
Decrease
-1.26
1LZ1
I56V
0.38
64.90
2.70
-1.20
Decrease
-1.17
1LZ1
I56V
0.38
64.90
2.70
-1.20
Decrease
-1.17
1LZ1
I59A
1.62
49.20
2.70
-1.32
Decrease
-3.20
1LZ1
I59A
1.62
64.90
2.70
-1.72
Decrease
-3.10
1LZ1
I59A
1.62
64.90
2.70
-1.72
Decrease
-3.10
1LZ1
I59F
1.62
64.90
2.70
-0.81
Decrease
-1.62
1LZ1
I59G
1.62
64.90
2.70
-3.83
Decrease
-2.71
1LZ1
I59G
1.62
64.90
2.70
-3.83
Decrease
-2.71
1LZ1
I59L
1.62
64.90
2.70
0.00
Decrease
-0.17
1LZ1
I59M
1.62
64.90
2.70
-1.29
Decrease
-1.34
1LZ1
I59S
1.62
64.90
2.70
-3.59
Decrease
-2.26
1LZ1
I59T
1.62
64.90
2.70
-2.22
Decrease
-3.37
1LZ1
I59V
1.46
49.20
2.70
-0.93
Decrease
-0.71
1LZ1
I59V
1.62
64.90
2.70
-1.10
Decrease
-0.65
1LZ1
I59V
1.62
64.90
2.70
-1.10
Decrease
-0.65
1LZ1
I59Y
1.62
64.90
2.70
-3.78
Decrease
-2.30
1LZ1
I89A
2.92
64.90
2.70
-2.70
Decrease
-2.30
1LZ1
I89V
2.86
49.20
2.70
-0.35
Decrease
-1.15
1LZ1
I89V
2.92
64.90
2.70
-0.48
Decrease
-1.03
1LZ1
P71G
54.05
68.80
2.80
-1.60
Decrease
-1.47
1LZ1
Q58A
7.22
64.90
2.70
0.91
Decrease
-0.00
1LZ1
Q58G
7.22
64.90
2.70
1.87
Decrease
-1.01
1LZ1
Q58G
7.22
64.90
2.70
1.87
Decrease
-1.01
1LZ1
R21A
63.62
64.90
2.70
1.32
Decrease
0.40
1LZ1
R21G
63.62
64.90
2.70
1.15
Decrease
0.03
1LZ1
R50A
61.62
64.90
2.70
0.43
Increase
0.06
1LZ1
R50G
61.62
64.90
2.70
0.26
Decrease
0.33
1LZ1
R50G
61.62
64.90
2.70
0.26
Decrease
0.33
1LZ1
V74A
60.70
64.90
2.70
-0.36
Decrease
-0.47
1LZ1
V74A
62.39
49.20
2.70
-0.43
Decrease
-0.59
1LZ1
V74D
60.70
64.90
2.70
-0.43
Decrease
-0.33
1LZ1
V74F
60.70
64.90
2.70
-0.29
Decrease
-0.40
1LZ1
V74G
60.70
64.90
2.70
-0.22
Decrease
-0.84
1LZ1
V74I
60.70
64.90
2.70
0.45
Decrease
0.41
1LZ1
V74L
60.70
64.90
2.70
0.19
Decrease
-0.06
1LZ1
V74M
60.70
64.90
2.70
0.65
Decrease
0.05
1LZ1
V74N
60.70
64.90
2.70
-0.33
Decrease
-0.36
1LZ1
V74R
60.70
64.90
2.70
-0.07
Decrease
0.17
1LZ1
V74S
60.70
64.90
2.70
-0.38
Decrease
-0.41
1LZ1
V74S
60.70
64.90
2.70
-0.38
Decrease
-0.41
1LZ1
V74Y
60.70
64.90
2.70
-0.24
Decrease
-0.33
1LZ1
V93A
2.47
64.90
2.70
-0.74
Decrease
-1.00
1LZ1
V93A
2.86
49.20
2.70
-1.00
Decrease
-1.24
1LZ1
V93T
2.47
64.90
2.70
-0.67
Decrease
-1.18
1LZ1
V99A
1.69
64.90
2.70
-0.98
Decrease
-0.36
1LZ1
V99A
2.21
49.20
2.70
-0.89
Decrease
-0.65
1LZ1
V99T
1.69
64.90
2.70
-0.50
Decrease
-0.59
1LZ1
Y20F
23.82
64.90
2.70
-0.50
Decrease
-0.50
1LZ1
Y38A
8.42
64.90
2.70
-2.49
Decrease
-1.68
1LZ1
Y38F
8.42
64.90
2.70
-0.19
Decrease
-0.32
1LZ1
Y38G
8.42
64.90
2.70
-2.32
Decrease
-4.34
1LZ1
Y45F
58.73
64.90
2.70
0.07
Increase
0.24
1LZ1
Y54F
8.19
64.90
2.70
-0.96
Decrease
-1.13
1LZ1
Y63F
52.46
64.90
2.70
-0.24
Decrease
-0.81
1LZ1
D102N
34.84
65.00
2.20
0.17
Decrease
0.21
1LZ1
D102N
34.84
65.00
2.30
0.14
Decrease
0.21
1LZ1
D102N
34.84
65.00
4.00
-0.67
Decrease
0.13
1LZ1
D102N
34.84
65.00
4.50
0.07
Decrease
0.10
1LZ1
D120N
64.33
65.00
2.20
0.10
Increase
0.35
1LZ1
D120N
64.33
65.00
2.30
0.19
Increase
0.34
1LZ1
D120N
64.33
65.00
4.00
-0.67
Increase
0.23
1LZ1
D120N
64.33
65.00
4.50
0.05
Increase
0.19
1LZ1
I106A
2.54
64.90
2.70
-0.93
Decrease
-2.08
1LZ1
I106V
2.54
64.90
2.70
-0.72
Decrease
0.44
1LZ1
I106V
7.03
49.20
2.70
-0.98
Decrease
0.29
1LZ1
N118A
102.25
64.90
2.70
0.19
Increase
-0.13
1LZ1
N118G
102.25
64.90
2.70
0.05
Decrease
-0.08
1LZ1
P103G
103.17
68.80
2.80
-0.10
Decrease
-0.95
1LZ1
V100A
0.59
49.20
2.70
-0.57
Decrease
-1.19
1LZ1
V100A
0.59
64.90
2.70
-0.26
Decrease
-0.93
1LZ1
V100F
0.59
64.90
2.70
-1.65
Decrease
-0.52
1LZ1
V100T
0.59
64.90
2.70
-0.29
Decrease
0.47
1LZ1
V110A
60.12
64.90
2.70
0.53
Increase
-0.10
1LZ1
V110A
61.87
49.20
2.70
0.07
Increase
-0.25
1LZ1
V110D
60.12
64.90
2.70
0.17
Increase
0.11
1LZ1
V110F
60.12
64.90
2.70
-0.05
Increase
-0.07
1LZ1
V110G
60.12
64.90
2.70
0.48
Increase
0.13
1LZ1
V110I
60.12
64.90
2.70
0.86
Increase
1.08
1LZ1
V110L
60.12
64.90
2.70
0.07
Increase
1.02
1LZ1
V110M
60.12
64.90
2.70
0.53
Increase
0.75
1LZ1
V110N
60.12
64.90
2.70
0.07
Increase
-0.24
1LZ1
V110P
60.12
68.80
2.80
0.50
Increase
-0.67
1LZ1
V110R
60.12
64.90
2.70
0.89
Increase
0.55
1LZ1
V110Y
60.12
64.90
2.70
-0.14
Increase
0.49
1LZ1
V121A
10.74
64.90
2.70
-1.44
Decrease
-1.05
1LZ1
V121A
14.18
49.20
2.70
-1.75
Decrease
-1.23
1LZ1
V125A
18.41
64.90
2.70
-1.32
Decrease
-1.06
1LZ1
V125A
20.43
49.20
2.70
-1.60
Decrease
-1.30
1LZ1
V130A
39.43
49.20
2.70
-1.12
Decrease
-1.54
1LZ1
V130A
46.52
64.90
2.70
-0.84
Decrease
-1.16
1LZ1
Y124F
8.75
64.90
2.70
-0.36
Decrease
0.16
1MBG
V103A
0.00
25.00
7.50
-2.32
Decrease
-1.15
1MBG
V103I
0.00
25.00
7.50
0.69
Decrease
0.56
1MBG
V103L
0.00
25.00
7.50
2.44
Decrease
-1.45
1N0J
I58T
57.35
70.00
7.80
-2.70
Decrease
-1.16
1ONC
M23L
0.00
25.00
2.00
-2.51
Decrease
-1.65
1ONC
M23L
0.00
25.00
2.50
-2.30
Decrease
-1.68
1ONC
M23L
0.00
25.00
3.00
-2.78
Decrease
-1.72
1ONC
M23L
0.00
25.00
3.50
-2.89
Decrease
-1.76
1ONC
M23L
0.00
25.00
4.00
-2.42
Decrease
-1.79
1ONC
M23L
0.00
25.00
5.00
-2.66
Decrease
-1.85
1ONC
M23L
0.00
25.00
6.00
-2.66
Decrease
-1.92
1ONC
M23L
0.00
25.00
7.00
-2.22
Decrease
-1.99
1ONC
M23L
0.00
25.00
8.00
-2.39
Decrease
-2.04
1OTR
V5A
0.00
50.00
3.75
-3.01
Decrease
-2.68
1OTR
V5N
0.00
50.00
3.75
-5.38
Decrease
-4.44
1OTR
V5T
0.00
50.00
3.75
-3.73
Decrease
-2.11
1OTR
E34C
41.67
65.00
3.00
0.91
Increase
-0.13
1OTR
E34G
41.67
65.00
3.00
1.39
Increase
-1.23
1OTR
E34H
41.67
65.00
3.00
-3.92
Increase
0.22
1OTR
E34I
41.67
65.00
3.00
1.65
Increase
1.34
1OTR
E34K
41.67
65.00
3.00
-2.15
Increase
0.06
1OTR
E34L
41.67
65.00
3.00
1.36
Increase
-0.03
1OTR
E34P
41.67
65.00
3.00
-2.13
Increase
0.27
1OTR
E34Q
41.67
65.00
3.00
-1.46
Increase
0.47
1OTR
E34S
41.67
65.00
3.00
0.12
Increase
-0.40
1OTR
E34T
41.67
65.00
3.00
1.51
Increase
0.49
1OTR
E34W
41.67
65.00
3.00
1.32
Increase
0.18
1OTR
I30L
0.00
50.00
3.00
-1.96
Decrease
-1.45
1OTR
I36F
15.62
50.00
3.00
-0.86
Decrease
-1.13
1OTR
I36L
15.62
50.00
3.00
-1.32
Decrease
-0.35
1OTR
I36V
15.62
50.00
3.00
-0.79
Decrease
-1.46
1OTR
L67A
0.05
50.00
3.75
-2.82
Decrease
-2.60
1OTR
L67N
0.05
50.00
3.75
-3.40
Decrease
-3.37
1OTR
L67S
0.05
50.00
3.75
-3.30
Decrease
-2.54
1OTR
L67T
0.05
50.00
3.75
-2.92
Decrease
-3.85
1OTR
Q41L
0.11
50.00
3.75
-0.26
Decrease
-0.17
1OTR
Q41N
0.11
50.00
3.75
-2.56
Decrease
-1.68
1OTR
Q41S
0.11
50.00
3.75
-1.27
Decrease
-1.22
1OTR
Q41T
0.11
50.00
3.75
-0.43
Decrease
-1.74
1OTR
Q41V
0.11
50.00
3.75
-0.05
Decrease
-0.15
1OTR
V17A
1.82
50.00
3.75
-1.63
Decrease
-2.43
1OTR
V17N
1.82
50.00
3.75
-4.90
Decrease
-4.06
1OTR
V17T
1.82
50.00
3.75
-1.89
Decrease
-3.10
1PGA
D46A
38.45
25.00
7.00
-1.36
Decrease
-0.23
1PGA
D47A
79.11
25.00
7.00
0.36
Decrease
-0.52
1PGA
K50A
57.17
25.00
7.00
-0.45
Decrease
-0.39
1PGA
T49A
71.16
25.00
7.00
-0.86
Decrease
-0.58
1PGA
T53C
20.98
60.00
5.20
0.78
Increase
0.22
1PGA
T53D
20.98
60.00
5.20
-0.85
Increase
1.08
1PGA
T53E
20.98
60.00
5.20
0.23
Increase
0.84
1PGA
T53F
20.98
60.00
5.20
1.08
Increase
2.95
1PGA
T53G
20.98
60.00
5.20
-1.21
Increase
-0.19
1PGA
T53H
20.98
60.00
5.20
0.37
Increase
-0.26
1PGA
T53I
20.98
60.00
5.20
1.25
Increase
2.56
1PGA
T53K
-29.13
60.00
5.20
0.35
Increase
-0.75
1PGA
T53L
20.98
60.00
5.20
0.45
Increase
0.91
1PGA
T53M
20.98
60.00
5.20
0.90
Increase
1.05
1PGA
T53N
20.98
60.00
5.20
0.52
Increase
0.88
1PGA
T53Q
20.98
60.00
5.20
0.38
Increase
0.02
1PGA
T53R
20.98
60.00
5.20
0.40
Increase
0.47
1PGA
T53S
20.98
60.00
5.20
0.87
Increase
1.45
1PGA
T53T
20.98
60.00
5.20
1.36
Increase
1.25
1PGA
T53V
20.98
60.00
5.20
0.94
Increase
2.29
1PGA
T53W
20.98
60.00
5.20
1.04
Increase
1.01
1PGA
T53Y
20.98
60.00
5.20
1.63
Increase
3.04
1PGA
V54A
0.07
25.00
7.00
-0.10
Decrease
-1.66
1POH
K49A
44.53
25.00
7.00
1.60
Increase
0.23
1POH
K49D
44.53
25.00
7.00
1.80
Increase
0.18
1POH
K49E
44.53
25.00
7.00
2.10
Increase
0.73
1POH
K49E
44.53
30.00
7.00
1.90
Increase
0.72
1POH
K49E
44.53
63.40
7.00
2.10
Increase
0.55
1POH
K49G
44.53
25.00
7.00
1.20
Increase
-0.57
1POH
K49M
44.53
25.00
7.00
1.00
Increase
1.29
1POH
K49N
44.53
25.00
7.00
0.40
Increase
0.88
1POH
K49Q
44.53
25.00
7.00
1.50
Increase
0.76
1POH
K49R
44.53
25.00
7.00
-0.20
Increase
1.08
1POH
K49S
44.53
25.00
7.00
1.20
Increase
1.37
1POH
S46A
27.13
30.00
7.00
-0.90
Increase
1.29
1POH
S46A
27.13
30.00
7.00
-1.10
Increase
1.29
1POH
S46D
27.13
30.00
7.00
1.40
Increase
-0.45
1POH
S46D
27.13
30.00
7.00
1.50
Increase
-0.45
1POH
S46N
27.13
30.00
7.00
0.30
Increase
-0.09
1POH
S46N
27.13
30.00
7.00
0.50
Increase
-0.09
1RN1
N9A
30.05
25.00
7.00
-0.90
Decrease
-1.65
1RN1
N9A
30.05
50.90
7.00
-0.71
Decrease
-1.35
1RN1
A21C
55.44
0.00
2.50
-0.74
Decrease
-0.47
1RN1
A21D
55.44
0.00
2.50
0.33
Decrease
-0.48
1RN1
A21D
55.44
0.00
7.00
-0.71
Decrease
-0.55
1RN1
A21E
55.44
0.00
2.50
0.05
Decrease
-0.30
1RN1
A21E
55.44
0.00
7.00
-0.69
Decrease
-0.42
1RN1
A21F
55.44
0.00
2.50
-0.57
Decrease
-0.07
1RN1
A21G
55.44
0.00
2.50
-0.90
Decrease
-1.21
1RN1
A21H
55.44
0.00
2.50
-0.56
Decrease
-1.21
1RN1
A21H
55.44
0.00
7.00
-0.17
Decrease
-1.32
1RN1
A21I
55.44
0.00
2.50
-0.44
Decrease
-0.34
1RN1
A21K
55.44
0.00
2.50
-0.51
Decrease
-0.31
1RN1
A21L
55.44
0.00
2.50
-0.13
Decrease
0.27
1RN1
A21M
55.44
0.00
2.50
-0.15
Decrease
-0.81
1RN1
A21N
55.44
0.00
2.50
0.34
Decrease
-0.60
1RN1
A21Q
55.44
0.00
2.50
-0.26
Decrease
-0.58
1RN1
A21Q
55.44
0.00
7.00
-0.40
Decrease
-0.69
1RN1
A21R
55.44
0.00
2.50
-0.41
Decrease
-0.43
1RN1
A21S
55.44
0.00
2.50
-0.49
Decrease
-0.52
1RN1
A21S
55.44
0.00
7.00
-0.40
Decrease
-0.73
1RN1
A21T
55.44
0.00
2.50
-0.57
Decrease
-0.75
1RN1
A21V
55.44
0.00
2.50
-0.66
Decrease
0.05
1RN1
A21W
55.44
0.00
2.50
-0.30
Decrease
0.39
1RN1
A21Y
55.44
0.00
2.50
-0.39
Decrease
-0.08
1RN1
D49H
100.49
25.00
7.00
1.10
Decrease
-0.51
1RN1
D76A
2.36
15.00
7.00
-3.70
Decrease
-2.77
1RN1
D76A
2.36
15.00
7.00
-3.80
Decrease
-2.77
1RN1
D76N
2.36
15.00
7.00
-3.10
Decrease
-2.22
1RN1
D76N
2.36
15.00
7.00
-3.10
Decrease
-2.22
1RN1
D76S
2.36
15.00
7.00
-3.10
Decrease
-2.28
1RN1
D76S
2.36
15.00
7.00
-3.30
Decrease
-2.28
1RN1
E58A
4.69
25.00
7.00
-0.77
Decrease
-1.10
1RN1
E58A
4.69
48.60
7.00
-0.78
Decrease
-0.81
1RN1
H40T
36.34
25.00
6.00
-0.26
Decrease
-0.57
1RN1
H92A
21.33
25.00
6.00
-0.62
Decrease
-0.53
1RN1
N36A
46.31
25.00
7.00
0.03
Decrease
-0.91
1RN1
N36A
46.31
50.90
7.00
0.00
Increase
-0.59
1RN1
N44A
33.95
25.00
7.00
-2.08
Decrease
-1.72
1RN1
N44A
33.95
50.80
7.00
-1.60
Decrease
-1.70
1RN1
N44A
33.95
50.90
7.00
-1.86
Decrease
-1.70
1RN1
N44D
33.95
50.80
7.00
-1.60
Decrease
-0.73
1RN1
N44S
33.95
50.80
7.00
-1.50
Decrease
-1.51
1RN1
N81A
3.96
25.00
7.00
-2.87
Decrease
-1.62
1RN1
N81A
3.96
50.90
7.00
-2.91
Decrease
-1.40
1RN1
Q25K
53.08
25.00
7.00
0.94
Decrease
-0.00
1RN1
Q25K
53.08
48.60
7.00
0.93
Increase
0.23
1RN1
S12A
37.46
25.00
7.00
-1.23
Decrease
-1.49
1RN1
S12A
37.46
50.90
7.00
-1.08
Decrease
-1.51
1RN1
S17A
53.50
25.00
7.00
0.67
Decrease
-0.35
1RN1
S17A
53.50
50.90
7.00
0.57
Decrease
-0.18
1RN1
S64A
72.01
25.00
7.00
-1.44
Decrease
-1.25
1RN1
S64A
72.01
50.90
7.00
-1.56
Decrease
-1.11
1RN1
W59Y
0.75
25.00
6.00
-0.93
Decrease
-1.53
1RN1
Y11F
2.76
25.00
7.00
-2.11
Decrease
-1.49
1RN1
Y11F
2.76
50.90
7.00
-2.03
Decrease
-1.43
1RN1
Y24W
16.66
25.00
6.00
1.24
Decrease
-0.43
1RN1
Y42F
6.50
25.00
7.00
1.14
Decrease
-0.77
1RN1
Y42F
6.50
50.90
7.00
1.15
Decrease
-0.74
1RN1
Y42W
6.50
25.00
6.00
-0.14
Decrease
0.25
1RN1
Y45W
59.66
25.00
6.00
0.74
Decrease
-0.87
1RN1
Y56F
11.37
25.00
7.00
-0.78
Decrease
0.46
1RN1
Y56F
11.37
50.90
7.00
-0.71
Decrease
0.51
1RN1
Y57F
6.32
25.00
7.00
-0.50
Decrease
-0.42
1RN1
Y57F
6.32
50.90
7.00
-0.44
Decrease
-0.35
1RN1
Y68F
3.74
25.00
7.00
-1.36
Decrease
-1.16
1RN1
Y68F
3.74
50.90
7.00
-1.35
Decrease
-0.99
1ROP
D30A
87.44
69.00
7.00
0.30
Increase
1.11
1ROP
D30C
87.44
69.00
7.00
0.80
Increase
-0.11
1ROP
D30E
87.44
69.00
7.00
1.00
Increase
0.51
1ROP
D30F
87.44
69.00
7.00
-0.10
Increase
0.53
1ROP
D30G
87.44
69.00
7.00
2.00
Increase
-0.02
1ROP
D30H
87.44
69.00
7.00
0.90
Increase
0.56
1ROP
D30I
87.44
69.00
7.00
-0.80
Increase
0.63
1ROP
D30K
87.44
69.00
7.00
0.90
Increase
0.13
1ROP
D30L
87.44
69.00
7.00
-0.10
Increase
0.63
1ROP
D30M
87.44
69.00
7.00
0.60
Increase
0.35
1ROP
D30N
87.44
69.00
7.00
0.80
Increase
0.61
1ROP
D30P
87.44
69.00
7.00
-1.60
Increase
-0.10
1ROP
D30Q
87.44
69.00
7.00
1.80
Increase
0.26
1ROP
D30R
87.44
69.00
7.00
0.80
Increase
0.62
1ROP
D30S
87.44
69.00
7.00
1.00
Increase
0.05
1ROP
D30T
87.44
69.00
7.00
-0.40
Increase
0.15
1ROP
D30V
87.44
69.00
7.00
-0.40
Increase
0.43
1ROP
D30W
87.44
69.00
7.00
-0.40
Increase
0.67
1ROP
D30Y
87.44
69.00
7.00
0.20
Increase
1.26
1ROP
L41A
46.53
25.00
6.00
-6.12
Decrease
-2.06
1ROP
L41V
46.53
25.00
6.00
-2.53
Decrease
-2.16
1RTB
P93A
73.29
56.05
4.20
-2.70
Decrease
-1.34
1RTB
P93G
73.29
61.60
6.00
-2.20
Decrease
-1.80
1RTB
P93G
73.29
61.80
6.00
-2.60
Decrease
-1.80
1RTB
P93S
73.29
56.05
4.20
-2.10
Decrease
-1.80
1RTB
Y97A
2.95
63.30
5.00
-12.00
Decrease
-4.74
1RTB
Y97F
2.95
63.30
5.00
-3.54
Decrease
-5.85
1RTB
Y97G
2.95
63.30
5.00
-11.70
Decrease
-5.41
1RTB
D121A
8.33
25.00
1.20
-0.72
Decrease
-2.13
1RTB
D121A
8.33
25.00
6.00
-2.20
Decrease
-2.60
1RTB
D121N
8.33
25.00
1.20
-0.76
Decrease
-1.23
1RTB
D121N
8.33
25.00
6.00
-1.90
Decrease
-1.47
1RTB
H119A
38.54
25.00
1.20
1.10
Decrease
-0.67
1RTB
H119A
38.54
25.00
6.00
0.20
Decrease
-0.95
1RTB
P114A
79.00
56.05
4.20
-3.20
Decrease
-1.02
1RTB
P114G
79.00
56.05
4.20
-2.80
Decrease
-1.59
1RTB
P114G
79.00
61.60
6.00
-3.30
Decrease
-1.57
1RTB
P114G
79.00
61.80
6.00
-3.60
Decrease
-1.57
1RX4
L28R
67.72
15.00
7.80
0.50
Decrease
-0.98
1RX4
V75A
7.94
15.00
7.80
-0.20
Decrease
-1.52
1RX4
V75C
7.94
15.00
7.80
-0.20
Decrease
-1.13
1RX4
V75H
7.94
15.00
6.50
-1.90
Decrease
-3.19
1RX4
V75H
7.94
15.00
7.80
-1.70
Decrease
-3.13
1RX4
V75I
7.94
15.00
7.80
-2.00
Decrease
-0.75
1RX4
V75R
7.94
15.00
7.80
-2.80
Decrease
-1.76
1RX4
V75S
7.94
15.00
7.80
-1.90
Decrease
-2.25
1RX4
V75Y
7.94
15.00
7.80
-2.30
Decrease
-1.56
1RX4
V88A
33.77
20.00
7.20
0.20
Decrease
-0.53
1RX4
V88I
33.77
20.00
7.20
-1.73
Decrease
-1.52
1RX4
E139K
42.36
15.00
7.80
-2.36
Decrease
-2.05
1RX4
E139Q
42.36
15.00
7.80
-1.36
Decrease
-0.64
1SAR
D25K
87.86
47.20
7.00
-0.90
Increase
-0.20
1SAR
E74K
80.48
47.20
7.00
-1.10
Decrease
-0.22
1SAR
N39A
11.68
48.40
7.00
-2.20
Decrease
-3.02
1SAR
N39D
11.68
48.40
7.00
-1.50
Decrease
-1.92
1SAR
N39S
11.68
48.40
7.00
-2.30
Decrease
-1.85
1SHG
F52Y
25.36
24.85
7.00
-0.44
Decrease
-0.13
1SHG
K18F
75.94
24.85
7.00
2.33
Increase
0.79
1SHG
K59F
52.65
24.85
7.00
0.92
Increase
0.58
1SHG
K59F
52.65
24.85
7.00
2.51
Increase
0.58
1SHG
K59Y
52.65
24.85
7.00
0.84
Increase
0.04
1SHG
Y13F
55.59
24.85
7.00
2.53
Decrease
-0.17
1SHG
Y13F
55.59
25.00
7.00
0.03
Decrease
-0.16
1SHG
Y57F
35.24
24.85
7.00
2.57
Decrease
-0.11
1SHG
Y57F
35.24
25.00
7.00
0.07
Decrease
-0.11
1STN
A60G
55.08
20.00
7.00
-1.50
Decrease
-1.22
1STN
A60V
55.08
20.00
7.00
-2.90
Increase
0.61
1STN
A90S
0.00
20.00
7.00
-2.00
Decrease
-2.38
1STN
A90S
0.00
47.00
5.00
-2.60
Decrease
-2.23
1STN
A90S
0.00
51.40
7.00
-2.50
Decrease
-2.18
1STN
D77A
2.50
20.00
7.00
-3.20
Decrease
-0.56
1STN
D77G
2.50
20.00
7.00
-2.20
Decrease
-1.70
1STN
D83A
24.71
20.00
7.00
-3.90
Decrease
-1.43
1STN
D83G
24.71
20.00
7.00
-2.80
Decrease
-2.08
1STN
D95A
39.42
20.00
7.00
-3.60
Decrease
-1.26
1STN
D95G
39.42
20.00
7.00
-3.10
Decrease
-1.34
1STN
E73A
26.22
20.00
7.00
-1.60
Decrease
-0.36
1STN
F61A
27.90
20.00
7.00
-2.40
Decrease
-1.69
1STN
F61G
27.90
20.00
7.00
-4.70
Decrease
-2.87
1STN
F76A
8.47
20.00
7.00
-4.10
Decrease
-2.90
1STN
F76G
8.47
20.00
7.00
-4.70
Decrease
-4.63
1STN
G79S
23.63
20.00
7.00
-2.40
Decrease
-0.58
1STN
G79S
23.63
40.00
5.28
-1.80
Decrease
-0.29
1STN
G79S
23.63
47.00
5.00
-1.20
Decrease
-0.19
1STN
G79S
23.63
51.40
7.00
-1.30
Decrease
-0.16
1STN
G88V
0.13
47.00
5.00
0.60
Decrease
-3.32
1STN
G88V
0.13
51.40
7.00
0.50
Decrease
-3.35
1STN
H46Y
21.06
40.00
5.38
0.00
Increase
1.84
1STN
I18G
26.54
20.00
7.00
-2.60
Decrease
-2.46
1STN
I18M
26.54
40.00
5.42
-0.20
Decrease
-0.13
1STN
L25A
0.00
47.00
5.00
-2.80
Decrease
-3.28
1STN
L25A
0.00
51.40
7.00
-2.60
Decrease
-3.18
1STN
L36A
0.00
20.00
7.00
-3.60
Decrease
-3.90
1STN
L36G
0.00
20.00
7.00
-5.40
Decrease
-4.64
1STN
L37A
7.10
20.00
7.00
-1.80
Decrease
-3.07
1STN
L37G
7.10
20.00
7.00
-3.90
Decrease
-4.99
1STN
L89F
14.15
40.00
5.38
-1.20
Decrease
0.89
1STN
T33S
24.59
20.00
7.00
-1.40
Decrease
-0.79
1STN
T62A
0.00
20.00
7.00
-2.40
Decrease
-2.44
1STN
T62G
0.00
20.00
7.00
-3.40
Decrease
-2.98
1STN
V23F
0.13
40.00
5.35
-1.50
Decrease
-2.30
1STN
V66L
1.50
47.00
5.00
0.60
Decrease
-1.10
1STN
V66L
1.50
51.40
7.00
0.80
Decrease
-1.14
1STN
Y91S
0.00
20.00
7.00
-5.30
Decrease
-2.30
1STN
H124L
50.69
40.00
5.20
0.70
Increase
1.27
1STN
H124L
50.69
47.00
5.00
1.90
Increase
1.33
1STN
H124L
50.69
51.40
7.00
1.30
Increase
1.24
1STN
L103A
0.00
20.00
7.00
-4.60
Decrease
-3.20
1STN
N118D
4.99
20.00
7.00
-2.50
Decrease
-1.73
1SUP
M50F
17.04
58.80
8.00
0.48
Decrease
-0.88
1SUP
N76D
61.48
58.80
8.00
0.45
Increase
0.02
1SUP
G169A
0.89
58.80
8.00
0.30
Decrease
-0.93
1SUP
N218S
60.18
58.80
8.00
1.07
Increase
0.58
1SUP
Q206C
36.17
58.80
8.00
1.25
Increase
-0.47
1SUP
Y217K
32.52
58.80
8.00
0.72
Decrease
-2.32
1TPK
V65A
0.13
64.30
4.50
-2.00
Decrease
-1.89
1TPK
V65I
0.13
64.30
4.50
0.30
Decrease
-1.06
1TPK
V65L
0.13
64.30
4.50
-1.90
Decrease
-0.41
1TPK
V65M
0.13
64.30
4.50
-2.20
Decrease
-0.99
1TPK
V65S
0.13
64.30
4.50
-2.40
Decrease
-1.67
1TPK
V65T
0.13
64.30
4.50
-1.00
Decrease
-1.28
1TUP
C242S
13.60
10.00
7.20
-2.94
Decrease
-0.14
1TUP
R175H
2.53
10.00
7.20
-3.01
Decrease
-1.48
1TUP
R248Q
84.76
10.00
7.20
-1.94
Decrease
-0.35
1TUP
R249S
11.48
10.00
7.20
-1.95
Decrease
-2.61
1TUP
R273H
32.05
10.00
7.20
-0.35
Decrease
-2.94
1VQB
I6V
0.59
25.00
7.00
-0.70
Decrease
-0.50
1VQB
A86T
89.29
25.00
7.00
-0.70
Decrease
-0.65
1VQB
A86V
89.29
25.00
7.00
0.50
Decrease
-1.28
1VQB
C33A
0.00
25.00
7.00
-0.50
Decrease
-3.31
1VQB
C33I
0.00
25.00
7.00
-0.90
Decrease
-1.07
1VQB
C33L
0.00
25.00
7.00
-2.60
Decrease
-1.68
1VQB
C33M
0.00
25.00
7.00
-3.50
Decrease
-0.89
1VQB
C33S
0.00
25.00
7.00
-4.20
Decrease
-2.21
1VQB
C33S
0.00
25.00
7.00
-4.30
Decrease
-2.21
1VQB
C33T
0.00
25.00
7.00
-4.60
Decrease
-3.39
1VQB
C33V
0.00
25.00
7.00
-0.20
Decrease
-1.76
1VQB
D36C
34.42
25.00
7.00
-2.00
Decrease
-2.16
1VQB
D36C
34.42
25.00
7.00
-2.10
Decrease
-2.16
1VQB
D36N
34.42
25.00
7.00
-1.00
Decrease
-1.72
1VQB
D50H
28.52
25.00
7.00
-1.50
Decrease
-1.09
1VQB
D50H
28.52
25.00
7.00
-1.60
Decrease
-1.09
1VQB
E30F
16.94
25.00
7.00
2.00
Decrease
0.03
1VQB
E30F
16.94
25.00
7.00
2.10
Decrease
0.03
1VQB
E30M
16.94
25.00
7.00
0.60
Decrease
0.22
1VQB
E30M
16.94
25.00
7.00
0.70
Decrease
0.22
1VQB
E30N
16.94
25.00
7.00
-1.10
Decrease
-0.38
1VQB
E40C
93.59
25.00
7.00
-1.60
Decrease
-0.83
1VQB
E40T
93.59
25.00
7.00
-0.40
Decrease
-0.94
1VQB
F13T
41.26
25.00
7.00
-0.70
Decrease
-2.38
1VQB
F68L
31.39
25.00
7.00
-4.20
Decrease
-2.62
1VQB
F68L
31.39
25.00
7.00
-4.30
Decrease
-2.62
1VQB
F68V
31.39
25.00
7.00
-5.00
Decrease
-2.05
1VQB
F73W
88.24
25.00
7.00
0.80
Decrease
-1.29
1VQB
H64C
43.05
25.00
7.00
0.50
Decrease
-2.01
1VQB
I47A
2.43
25.00
7.00
-7.00
Decrease
-3.87
1VQB
I47A
2.43
25.00
7.00
-7.10
Decrease
-3.87
1VQB
I47C
2.43
25.00
7.00
-5.20
Decrease
-3.83
1VQB
I47C
2.43
25.00
7.00
-5.30
Decrease
-3.83
1VQB
I47F
2.43
25.00
7.00
-1.90
Decrease
-3.38
1VQB
I47F
2.43
25.00
7.00
-2.00
Decrease
-3.38
1VQB
I47L
2.43
25.00
7.00
-0.60
Decrease
-3.11
1VQB
I47L
2.43
25.00
7.00
-0.70
Decrease
-3.11
1VQB
I47M
2.43
25.00
7.00
-2.10
Decrease
-3.62
1VQB
I47M
2.43
25.00
7.00
-2.20
Decrease
-3.62
1VQB
I47T
2.43
25.00
7.00
-7.40
Decrease
-5.03
1VQB
I47V
2.43
25.00
7.00
-2.50
Decrease
-1.67
1VQB
I47V
2.43
25.00
7.00
-2.60
Decrease
-1.67
1VQB
I78C
49.51
25.00
7.00
-4.40
Decrease
-3.43
1VQB
I78T
49.51
25.00
7.00
-6.60
Decrease
-2.87
1VQB
I78V
49.51
25.00
7.00
-1.30
Decrease
-1.22
1VQB
K24V
76.76
25.00
7.00
0.80
Increase
0.18
1VQB
K69H
42.15
25.00
7.00
-1.20
Decrease
-0.72
1VQB
K69H
42.15
25.00
7.00
-1.30
Decrease
-0.72
1VQB
K69M
42.15
25.00
7.00
0.10
Increase
-0.56
1VQB
K69M
42.15
25.00
7.00
0.20
Increase
-0.56
1VQB
L28V
34.35
25.00
7.00
1.10
Decrease
-1.56
1VQB
L32H
43.15
25.00
7.00
-0.90
Decrease
-1.67
1VQB
L32R
43.15
25.00
7.00
-1.60
Decrease
-0.66
1VQB
L32W
43.15
25.00
7.00
2.80
Decrease
-0.49
1VQB
L32Y
43.15
25.00
7.00
1.00
Decrease
-0.60
1VQB
L37A
63.24
25.00
7.00
-7.70
Decrease
-2.55
1VQB
L37C
63.24
25.00
7.00
-4.60
Decrease
-3.33
1VQB
L37I
63.24
25.00
7.00
-1.40
Decrease
-1.74
1VQB
L37T
63.24
25.00
7.00
-5.20
Decrease
-4.08
1VQB
L37V
63.24
25.00
7.00
-3.50
Decrease
-1.29
1VQB
L49A
4.92
25.00
7.00
-6.10
Decrease
-3.20
1VQB
L49C
4.92
25.00
7.00
-4.10
Decrease
-3.55
1VQB
L49I
4.92
25.00
7.00
-1.90
Decrease
-2.04
1VQB
L49T
4.92
25.00
7.00
-5.70
Decrease
-3.36
1VQB
L49V
4.92
25.00
7.00
-2.90
Decrease
-1.40
1VQB
L65P
84.16
25.00
7.00
-1.50
Decrease
-1.64
1VQB
L81C
11.58
25.00
7.00
-3.70
Decrease
-3.22
1VQB
L81T
11.58
25.00
7.00
-5.10
Decrease
-4.90
1VQB
L81V
11.58
25.00
7.00
-0.20
Decrease
-1.56
1VQB
M77A
44.83
25.00
7.00
-2.10
Decrease
-0.55
1VQB
M77C
44.83
25.00
7.00
0.00
Decrease
-1.66
1VQB
M77F
44.83
25.00
7.00
-0.20
Decrease
0.70
1VQB
M77I
44.83
25.00
7.00
1.60
Decrease
-1.12
1VQB
M77L
44.83
25.00
7.00
-1.20
Decrease
-0.47
1VQB
M77T
44.83
25.00
7.00
-0.80
Decrease
-0.60
1VQB
M77V
44.83
25.00
7.00
1.20
Decrease
-0.99
1VQB
R82C
22.14
25.00
7.00
-1.50
Decrease
-1.17
1VQB
S67C
0.00
25.00
7.00
-3.70
Decrease
-1.23
1VQB
S67T
0.00
25.00
7.00
-1.60
Decrease
-2.29
1VQB
T48C
13.84
25.00
7.00
-0.80
Decrease
-1.16
1VQB
T48V
13.84
25.00
7.00
0.00
Decrease
-0.89
1VQB
T62C
39.37
25.00
7.00
-0.70
Decrease
-1.00
1VQB
T62V
39.37
25.00
7.00
1.30
Decrease
-0.63
1VQB
V19C
65.71
25.00
7.00
-0.30
Decrease
-2.27
1VQB
V19T
65.71
25.00
7.00
-0.60
Decrease
-1.67
1VQB
V35A
5.53
25.00
7.00
-2.20
Decrease
-2.34
1VQB
V35A
5.53
25.00
7.00
-2.20
Decrease
-2.34
1VQB
V35C
5.53
25.00
7.00
-1.40
Decrease
-2.53
1VQB
V35C
5.53
25.00
7.00
-1.40
Decrease
-2.53
1VQB
V35F
5.53
25.00
7.00
-3.10
Decrease
-1.58
1VQB
V35F
5.53
25.00
7.00
-3.20
Decrease
-1.58
1VQB
V35I
5.53
25.00
7.00
-0.60
Decrease
-0.75
1VQB
V35I
5.53
25.00
7.00
-0.70
Decrease
-0.75
1VQB
V35L
5.53
25.00
7.00
-2.70
Decrease
-2.22
1VQB
V35L
5.53
25.00
7.00
-2.70
Decrease
-2.22
1VQB
V35M
5.53
25.00
7.00
-1.00
Decrease
-2.61
1VQB
V35M
5.53
25.00
7.00
-1.10
Decrease
-2.61
1VQB
V35T
5.53
25.00
7.00
-5.30
Decrease
-3.70
1VQB
V43C
36.11
25.00
7.00
-2.10
Decrease
-0.89
1VQB
V43T
36.11
25.00
7.00
-1.60
Decrease
-3.15
1VQB
V45A
32.27
25.00
7.00
-2.10
Decrease
-2.66
1VQB
V45C
32.27
25.00
7.00
-0.10
Decrease
-1.96
1VQB
V45L
32.27
25.00
7.00
-3.00
Decrease
-2.07
1VQB
V45T
32.27
25.00
7.00
-3.50
Decrease
-2.89
1VQB
V63C
15.35
25.00
7.00
-4.10
Decrease
-2.73
1VQB
V63T
15.35
25.00
7.00
-5.00
Decrease
-4.47
1VQB
V70C
68.05
25.00
7.00
-3.10
Decrease
-1.74
1VQB
V70C
68.05
25.00
7.00
-3.30
Decrease
-1.74
1VQB
V70P
68.05
25.00
7.00
-5.00
Decrease
-2.65
1VQB
V70P
68.05
25.00
7.00
-5.10
Decrease
-2.65
1VQB
V70T
68.05
25.00
7.00
-3.50
Decrease
-1.47
1VQB
Y26R
38.32
25.00
7.00
-0.40
Decrease
-0.69
1VQB
Y41A
79.60
25.00
7.00
-0.40
Decrease
-1.66
1VQB
Y41F
79.60
25.00
7.00
-0.60
Decrease
0.38
1YCC
F82Y
17.64
25.00
6.00
-0.70
Decrease
-0.25
1YCC
K73I
83.62
25.00
4.50
-0.40
Increase
0.94
1YCC
K73V
83.62
25.00
4.50
0.10
Increase
0.08
1YCC
K73W
83.62
25.00
4.50
-1.60
Increase
0.86
1YCC
L85A
4.81
25.00
6.00
-2.80
Decrease
-2.45
1YCC
N52A
11.48
26.85
4.60
0.63
Decrease
-0.51
1YCC
N52H
11.48
26.85
4.60
-1.27
Increase
0.06
1YCC
N52I
11.48
26.85
3.50
2.62
Increase
1.40
1YCC
N52I
11.48
26.85
4.00
3.03
Increase
1.39
1YCC
N52I
11.48
26.85
4.60
3.14
Increase
1.38
1YCC
N52I
11.48
26.85
5.00
2.02
Increase
1.36
1YCC
N52I
11.48
46.50
6.00
4.30
Increase
1.67
1YCC
N52I
19.60
37.00
4.60
3.14
Increase
1.68
1YCC
N52L
11.48
26.85
4.60
2.56
Increase
1.17
1YCC
N52M
11.48
26.85
4.00
2.91
Increase
1.31
1YCC
N52M
11.48
26.85
4.60
2.25
Increase
1.31
1YCC
N52Q
11.48
26.85
4.60
-0.08
Increase
0.00
1YCC
N52S
11.48
26.85
4.00
0.74
Increase
-0.11
1YCC
N52S
11.48
26.85
4.60
-0.05
Increase
-0.11
1YCC
N52S
11.48
26.85
5.00
-1.29
Increase
-0.11
1YCC
N52T
11.48
26.85
3.50
0.98
Increase
0.55
1YCC
N52T
11.48
26.85
4.00
1.01
Increase
0.54
1YCC
N52T
11.48
26.85
4.60
0.59
Increase
0.52
1YCC
N52T
11.48
26.85
5.00
-0.53
Increase
0.51
1YCC
N52V
11.48
26.85
4.00
2.44
Increase
0.67
1YCC
N52V
11.48
26.85
4.60
1.67
Increase
0.65
1YCC
P76G
70.82
25.00
4.60
-0.78
Decrease
-2.48
1YCC
P76L
70.82
25.00
4.60
-3.44
Decrease
0.66
1YCC
P76R
70.82
25.00
4.60
-0.97
Decrease
-1.78
1YCC
P76S
70.82
25.00
4.60
-1.89
Decrease
-2.09
1YCC
P76V
70.82
25.00
4.60
-1.07
Decrease
-1.83
1YCC
P76W
70.82
25.00
4.60
-2.38
Decrease
-1.13
1YCC
P76Y
70.82
25.00
4.60
-2.07
Decrease
-0.74
1YCC
C102A
0.85
46.50
6.00
2.90
Decrease
0.63
1YCC
C102S
0.85
46.50
6.00
2.80
Increase
-0.44
1YCC
C102T
0.85
51.40
4.70
0.50
Increase
2.06
1YCC
C102T
0.85
51.40
4.70
5.30
Increase
2.06
1YCC
C102T
0.85
57.10
6.00
0.80
Increase
2.10
1YCC
C102T
0.85
57.10
6.00
5.70
Increase
2.10
2ABD
A9G
8.17
5.00
5.30
-1.81
Decrease
-1.24
2ABD
F5A
0.00
5.00
5.30
-2.52
Decrease
-2.03
2ABD
A34G
6.35
5.00
5.30
-1.57
Decrease
-2.42
2ABD
D21A
18.46
5.00
5.30
0.42
Decrease
-1.69
2ABD
D21H
18.46
5.00
5.30
-0.56
Decrease
-0.83
2ABD
E67A
55.70
5.00
5.30
-0.36
Decrease
-0.89
2ABD
K32A
25.13
5.00
5.30
-1.02
Decrease
-1.28
2ABD
K32E
25.13
5.00
5.30
-1.68
Decrease
-1.69
2ABD
K32R
25.13
5.00
5.30
-1.83
Decrease
-0.67
2ABD
K52M
36.17
5.00
5.30
0.18
Increase
-0.09
2ABD
K54A
36.17
5.00
5.30
-0.86
Decrease
-0.36
2ABD
K54M
36.17
5.00
5.30
0.27
Increase
0.02
2ABD
L15A
0.33
5.00
5.30
-3.10
Decrease
-2.91
2ABD
L25A
8.74
5.00
5.30
-1.02
Decrease
-2.83
2ABD
L80A
1.80
5.00
5.30
-3.70
Decrease
-2.91
2ABD
P19A
4.51
5.00
5.30
-1.07
Decrease
-2.08
2ABD
P44A
35.66
5.00
5.30
-1.40
Decrease
-0.74
2ABD
Q33A
0.73
5.00
5.30
-3.66
Decrease
-0.09
2ABD
T35A
36.70
5.00
5.30
-1.09
Decrease
-1.04
2ABD
V12A
5.14
5.00
5.30
-1.69
Decrease
-1.49
2ABD
V77A
2.34
5.00
5.30
-1.14
Decrease
-1.55
2ABD
Y28A
24.85
5.00
5.30
-2.47
Decrease
-4.71
2ABD
Y28F
24.85
5.00
5.30
-1.06
Increase
0.77
2ABD
Y28N
24.85
5.00
5.30
-2.23
Decrease
-1.70
2ABD
Y31N
26.20
5.00
5.30
-1.52
Decrease
-2.35
2ABD
Y73A
1.59
5.00
5.30
-4.83
Decrease
-1.66
2ABD
Y73F
1.59
5.00
5.30
0.27
Decrease
-2.46
2AFG
L44P
0.00
40.05
6.60
0.69
Decrease
-2.40
2AFG
L73V
3.93
40.05
6.60
-1.46
Decrease
-1.66
2AFG
V109L
0.33
40.05
6.60
-0.57
Decrease
-0.81
2AKY
V8I
0.39
25.00
7.50
-1.20
Decrease
-0.05
2AKY
T77H
73.04
25.00
7.50
-2.15
Decrease
0.07
2AKY
I213F
0.00
25.00
7.50
-1.91
Decrease
-2.45
2AKY
N169D
49.66
25.00
7.50
-2.15
Decrease
-1.03
2CI2
A35G
0.00
25.00
6.25
-1.09
Decrease
-2.59
2CI2
A77G
40.02
25.00
6.30
-1.88
Decrease
-1.76
2CI2
D42A
41.78
25.00
6.25
-0.96
Decrease
-0.93
2CI2
D64A
21.24
25.00
6.25
-0.80
Decrease
-2.27
2CI2
D71A
40.94
25.00
6.25
-3.41
Decrease
-1.24
2CI2
E26A
50.20
25.00
6.25
-0.47
Decrease
-0.47
2CI2
E26Q
50.20
25.00
6.25
-0.62
Decrease
-0.24
2CI2
E33D
56.84
25.00
6.25
-0.52
Decrease
-0.76
2CI2
E33N
56.84
25.00
6.25
-0.70
Decrease
-1.34
2CI2
E33N
56.84
46.45
6.30
-0.70
Decrease
-1.31
2CI2
E33Q
56.84
25.00
6.25
-0.29
Decrease
-0.71
2CI2
E34D
50.72
25.00
6.25
-0.74
Decrease
-0.58
2CI2
E34N
50.72
25.00
6.25
-1.07
Decrease
-0.78
2CI2
E34Q
50.72
25.00
6.25
-0.47
Decrease
-0.38
2CI2
E45A
54.49
25.00
6.25
-0.32
Decrease
-0.82
2CI2
E45A
54.49
74.30
4.15
0.82
Decrease
0.20
2CI2
E60A
52.83
25.00
6.25
-0.70
Decrease
-0.25
2CI2
E60A
52.83
25.00
6.30
-0.68
Decrease
-0.25
2CI2
F69A
17.19
25.00
6.25
-3.84
Decrease
-3.38
2CI2